How Lamotrigine and Mood Stabilizers Work (or Not) for Borderline Personality Disorder

Living with Borderline Personality Disorder (BPD) can be a challenging journey, marked by fluctuating emotions and a range of symptoms. Many individuals with BPD turn to medication as part of their treatment plan, with doctors often prescribing mood stabilizers like Lamotrigine (Lamictal). However, the efficacy of these medications can vary widely from person to person. In this article, we explore the experiences of those who have relied on mood stabilizers for managing BPD, delve into the potential impact of these medications, and offer insights on their effectiveness.

Personal Experiences with Lamotrigine and Mood Stabilizers

Many people with BPD have tried a wide variety of medications over the years, often with mixed results. For instance, a user sharing their story on a support forum described being on Lamictal for eight years until 2020. Despite reaching the maximum recommended dose of 400 mg, they found that the medication did not provide the relief they hoped for. The user also mentioned trying numerous other medications, including SSRIs, antipsychotics, and SNRIs, without significant improvement.

The user detailed their gradual worsening condition, which included emotional instability, dissociative episodes, and an increase in hypomanic behavior. They also mentioned engaging in self-harm and experiencing multiple suicide attempts and hospitalizations. These experiences were hallmarks of a situation where medication was seemingly hindering rather than helping.

Upon discovering that medication was counterproductive, the user successfully weaned off the last medications in 2020 and 2021. Being in a treatment center during this process ensured safety as the user experienced significant withdrawal symptoms. After a period of detoxification and adjustment, they observed substantial improvements in their mental clarity, ability to rationalize, reduced impulsivity, and better emotional regulation. Over time, they also saw improvements in their short-term memory and dissociative symptoms, and they successfully stopped self-harming.

Another User's Perspective on Lamotrigine

A different user, who started using Lamotrigine at 300 mg two years ago, shared a much more positive experience. This individual found that the medication helped them significantly by providing stability and eliminating mood swings. They highlighted the fact that it takes time for the medication to work and settle in, but once it does, the benefits can be substantial. Interestingly, this user also mentioned seeing other positive reviews on Quora, indicating that the medication is well-regarded by many.

What the Research Says

While personal experiences are valuable, it's important to consider the broader research surrounding Lamotrigine and other mood stabilizers for BPD. Several studies have explored the use of Lamotrigine in treating BPD, with mixed results. For instance, a study published in the Journal of Clinical Psychiatry found that Lamotrigine can have a positive impact on mood stabilization, but its effectiveness can vary. Another study in the European Psychiatry journal highlighted the need for further research to determine the ideal dose and duration for treating BPD with Lamotrigine.

Research also underscores the importance of individual responses to medications. One meta-analysis of BPD treatment found that while some medications, including mood stabilizers, can help, they may not be effective for everyone. Factors such as the severity of symptoms, comorbid conditions, and personal history can all influence the response to medication.

Conclusion

The story of Lamotrigine and BPD is one of mixed results, reflecting the unique experiences of individuals and the complex nature of the disorder. While some people find significant relief and stability through the use of mood stabilizers, others may experience worsening conditions. It is crucial for individuals with BPD to work closely with healthcare providers to find the best treatment approach, which may involve a combination of medications, therapy, and lifestyle changes.

Understanding the potential benefits and limitations of Lamotrigine can empower individuals to make informed decisions about their treatment. If you or someone you know is considering the use of Lamotrigine or other mood stabilizers for BPD, it is essential to engage in open discussions with healthcare professionals to ensure the best possible outcomes.