Obtaining Syngeneic Mouse Ovarian Cancer ID8 Cell Lines for Research

When conducting biological research, access to specific and reliable cell lines is crucial for achieving accurate and meaningful results. One valuable type of cell line used in research is the syngeneic mouse ovarian cancer ID8. This particular cell line is widely recognized and has been extensively characterized, making it a preferred choice for various studies, particularly cancer research. In this article, we explore the different sources and methods for acquiring these cell lines, ensuring that your research is supported with the necessary tools and data.

Understanding Syngeneic Mouse Ovarian Cancer ID8 Cell Lines

Syngeneic mouse ovarian cancer ID8 cell lines are derived from spontaneous ovarian tumors in immunocompetent mouse strains. These cell lines are particularly useful because they closely mimic the human tumor microenvironment, allowing for more reliable and accurate preclinical trials. The ID8 cells are typically associated with a specific genetic background that makes them ideal for studying tumor biology, tumor heterogeneity, and the efficacy of different therapeutic approaches.

Where to Obtain ID8 Cell Lines

Obtaining ID8 cell lines can be challenging, but there are several reliable sources that can assist you in acquiring these valuable resources.

MI Bioresearch

MI Bioresearch offers both the original ID8 cell line and ID8 variants that express luciferase. Luciferase expression is particularly useful for monitoring tumor growth through bioluminescent imaging, making it a valuable tool in preclinical studies. However, it's worth noting that the use of luciferase-expressing cell lines for monitoring late-stage tumor growth has been questioned due to potential inaccuracies in the late stages of the disease.

If you require high-quality, authentic ID8 cell lines for your research, MI Bioresearch is an excellent source to consult.

Contacting Research Institutions

For researchers seeking additional options, another avenue is to reach out to those conducting related research. Here are some specific contacts and institutions you can consider:

Katherine F. Roby, PhD, at the University of Kansas Medical Center

Dr. Roby is a distinguished researcher in the field of ovarian cancer. She has extensive experience with the ID8 cell line and may be able to provide you with the specific cell lines or assist you in obtaining them through collaborative research. Contacting her directly can provide you with direct access to these valuable resources and potentially valuable research collaborations.

George Coukos, at Ludwig Cancer Research

Dr. Coukos is another leading researcher in the field of ovarian cancer. He has contributed significantly to the understanding of ovarian cancer biology and may have access to the ID8 cell lines or be able to direct you to an appropriate source. Reaching out to him can provide you with access to cutting-edge research and valuable resources.

Conclusion

The availability of syngeneic mouse ovarian cancer ID8 cell lines is essential for conducting accurate and meaningful research. MI Bioresearch, the University of Kansas Medical Center, and Ludwig Cancer Research are all reliable sources that can provide you with the appropriate cell lines. By ensuring access to these resources, your research will be better positioned for success

For more information or assistance with obtaining these valuable resources, please do not hesitate to contact the relevant institutions or researchers directly. Your research will greatly benefit from the availability of these high-quality cell lines.