Post-H. Pylori Eradication: Medicines for Stomach Ulcer Management

Introduction: After eradicating Helicobacter pylori (H. pylori), several medications may be prescribed to manage stomach ulcers, including proton pump inhibitors (PPIs), H2-receptor antagonists, and antacids. However, the necessity of continuing these treatments after H. pylori eradication can vary. Medications Post-Eradication: For severe cases, proton pump inhibitors (PPIs) might be required, while milder cases can be managed with H2-receptor antagonists. Antacids can also be used in certain situations. These medications help reduce stomach acid production and promote the healing of ulcerated tissue. Follow-Up and Consultation: It is crucial to follow up with a healthcare provider for ongoing management. Continual monitoring and consultation with a gastroenterologist or primary care physician are essential for determining the appropriate treatment plan. Recurrence Rates: Recurrence of H. pylori is a significant concern. According to a study by Hu Y et al. (2017), the global rate of H. pylori recurrence was 4.3%. The probability of recurrence is inversely related to the Human Development Index (HDI) and directly related to the prevalence of H. pylori in a country. Factors Influencing Recurrence: Socioeconomic factors and sanitary conditions play a crucial role in the recurrence of H. pylori. In very high HDI countries, the recurrence rate is 3.1%, while in low to medium HDI countries, it can reach up to 10.9%. This highlights the importance of addressing these underlying conditions to prevent recurrence. Conclusion: Post-H. pylori eradication, the choice of medication and the need for continued treatment depend on the severity of the ulcer and individual patient factors. Continuous medical follow-up and understanding the impact of socioeconomic factors can help in managing stomach ulcers effectively.

Keywords: stomach ulcer, H. pylori, proton pump inhibitors